H-Gly-Sar-Sar-OH_product_DataBase

Bioactivity	H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation[1][2][3].
In Vivo	H-Gly-Sar-Sar-OH (0.1 mM；灌注；单剂量) 在 Sprague-Dawley 大鼠肾脏中未显著被水解 (给药 60 min) 或清除[2]。H-Gly-Sar-Sar-OH (10 mg/kg；口服；单剂量) 在自发性高血压大鼠 (SHRs) 中显示出稳定性[3]。H-Gly-Sar-Sar-OH 在自发性高血压大鼠中的药代动力学 (PK) 参数[3]Week old
Name	H-Gly-Sar-Sar-OH
CAS	57836-11-0
Sequence	H-Gly-Sar-Sar-OH
Shortening	G-{Sar}-{Sar}
Formula	C8H15N3O4
Molar Mass	217.22
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Hong SM, et al. Structural Design of Oligopeptides for Intestinal Transport Model. J Agric Food Chem. 2016 Mar 16;64(10):2072-9. [2]. Minami H, et al. Oligopeptides: mechanism of renal clearance depends on molecular structure. Am J Physiol. 1992 Jul;263(1 Pt 2):F109-15. [3]. Hanh VT, et al. Effect of Aging on the Absorption of Small Peptides in Spontaneously Hypertensive Rats. J Agric Food Chem. 2017 Jul 26;65(29):5935-5943.

PeptideDB