Bioactivity | H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities[1]. |
CAS | 10270-94-7 |
Formula | C9H18N2O4 |
Molar Mass | 218.25 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Store at room temperature |
Reference | [1]. Rosowsky, et al. "Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain." Journal of medicinal chemistry 29.5 (1986): 655-660. |