PeptideDB

H-Dab(Boc)-OH

CAS: 10270-94-7 F: C9H18N2O4 W: 218.25

H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX
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Bioactivity H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities[1].
CAS 10270-94-7
Formula C9H18N2O4
Molar Mass 218.25
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature

Reference [1]. Rosowsky, et al. "Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain." Journal of medicinal chemistry 29.5 (1986): 655-660.