H-Arg-OtBu dihydrochloride_product_DataBase

Bioactivity	H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research[1].
In Vivo	H-Arg-OtBu (dihydrochloride) (0.3% solutions, 一天三次) 在兔角膜创面愈合模型中是否没有角膜炎症的迹象和炎症反应的证据[1]。H-Arg-OtBu (dihydrochloride) (0.3% solutions, 一天五次) 对金黄色葡萄球菌和 MRSA 的小鼠角膜感染模型有效[1]。
Name	H-Arg-OtBu dihydrochloride
CAS	87459-72-1
Formula	C10H24Cl2N4O2
Molar Mass	303.23
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Koh JJ, et al, Beuerman RW. Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections. J Med Chem. 2015 Jan 22;58(2):739-52.

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