| Bioactivity | H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP)-lowering activity. H-0106 dihydrochloride can effectively inhibit ROCK enzyme. H-0106 dihydrochloride demonstrated significant IOP-lowering effects in monkey eyes. Studies with H-0106 dihydrochloride suggest that there may not be a direct relationship between ROCK inhibition and IOP reduction[1]. |
| CAS | 1011465-90-9 |
| Formula | C16H22Cl3N3O2S |
| Molar Mass | 426.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys |
H-0106 dihydrochloride
CAS: 1011465-90-9 F: C16H22Cl3N3O2S W: 426.79
H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP)-lowering activity. H-0106 dihydrochlor
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