Bioactivity | H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition[1]. |
CAS | 913636-88-1 |
Formula | C15H20BrCl2N3O2S |
Molar Mass | 457.21 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys |