Bioactivity | Guanylyltransferase (GTase) plays a central role in the three-step catalytic process of adding an m7GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs)[1][2]. |
CAS | 593278-77-4 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Garg G, et al. Structural insights into human co-transcriptional capping. Mol Cell. 2023 Jul 20;83(14):2464-2477.e5. [2]. Chu C, et al. Structure of the guanylyltransferase domain of human mRNA capping enzyme. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10104-8. |