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Guanosine 5'-triphosphate-5'-adenosine triammonium

CAS: F: C20H36N13O17P3 W: 823.50

Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Gu
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Bioactivity Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog[1][2].
Invitro Guanosine 5'-triphosphate-5'-adenosine (GpppA) 在腺苷 3'-O 位上用芘标记后可作为人工底物。荧光标记的 GpppA triammonium 和 GpppG 类似物作为潜在底物,代表了酶的结构复杂性和需求之间的合理折中[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Guanosine 5'-triphosphate-5'-adenosine triammonium 相关抗体:
Formula C20H36N13O17P3
Molar Mass 823.50
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reference [1]. Renata Kasprzyk, et al. Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity. Chemistry. 2020 Sep 1;26(49):11266-11275. [2]. Dennis Reichert, et al. Light-control of cap methylation and mRNA translation via genetic code expansion of Ecm1. Chem Sci. 2021 Feb 8;12(12):4383-4388.