| Bioactivity | Grb2 SH2 domain inhibitor 1 TFA is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-l-pro motif ring (AF Φ Rpprrfq) (where Φ It is L-naphthylalanine, R is D-arginine, P is D-proline), which is mainly used as a cyclic peptide inhibitor. |
| Name | Grb2 SH2 domain inhibitor 1 TFA |
| Sequence | Cyclo(Tyr(PO3H2)-Arg-Arg-Pro-DPro-DArg-2Nal-Phe-Asn-Val) |
| Shortening | Cyclo(Tyr(PO3H2)-RRP-DPro-DArg-2Nal-FNV) |
| Formula | C68H95N20O15P.xC2HF3O2 |
| Molar Mass | 1463.58 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wen J,et al. Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif. Bioorg Med Chem. 2020 Oct 15;28(20):115711. |
Grb2 SH2 domain inhibitor 1 TFA
CAS: F: C68H95N20O15P.xC2HF3O2 W: 1463.58 (free base)
Grb2 SH2 domain inhibitor 1 TFA is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-
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