Bioactivity | Graveolide (Compound 5) is a sesquiterpenoid compound that can be isolated from C. abrotanoides. Graveolide possesses anti-inflammatory activity and can be utilized in the research of atopic dermatitis[1]. |
Invitro | Graveolide 在 RAW264.7 细胞中具有抗炎活性,IC50 值为 3.8 μM[1]。Graveolide (4-16 μM; 2 h) 在 LPS (HY-D1056) (1 μg/mL; 24 h) 诱导的 RAW264.7 细胞中能以剂量依赖方式显著降低 iNOS 和 COX-2 的蛋白质表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Graveolide 相关抗体: |
CAS | 72173-44-5 |
Formula | C15H20O3 |
Molar Mass | 248.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang XF, et al. Sesquiterpenoids from Carpesium abrotanoides and their anti-inflammatory activity both in vitro and in vivo. Bioorg Chem. 2024 Oct;151:107684. |