Bioactivity | GprA is a new synthetic agonist of G-protein-coupled receptor 120/free fatty acid receptor 4 (GPR120/FFAR4), with an AC50 of 203 nM on human GPR120 full isoform. GprA can be used in the research for NAFLD[1]. |
In Vivo | GprA 可以减少WSD (西式饮食) 喂养小鼠的脂肪变性迹象。GprA在减少胶原沉积和纤维化发展方面也有效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
Formula | C17H17NO3S |
Molar Mass | 315.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Simona Pompili, et al. G-Protein-Coupled Receptor 120 Agonist Mitigates Steatotic and Fibrotic Features Triggered in Obese Mice by the Administration of a High-Fat and High-Carbohydrate Diet. ACS OmegaVol 9/Issue 29. |