| Bioactivity | Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[1][2]. |
| Invitro | Goserelin (1 nM-1 mM; 48-72 hours) promots EOC cell apoptosis[1].Goserelin (100 μM; 24-72 hours) regulates the expression of human apoptosis-related genes in SKOV3-ip cells[1].Goserelin (100 μM; 24-72 hours) influences EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway[1]. Apoptosis Analysis[1] Cell Line: |
| Name | Goserelin |
| CAS | 65807-02-5 |
| Formula | C59H84N18O14 |
| Molar Mass | 1269.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Goserelin
CAS: 65807-02-5 F: C59H84N18O14 W: 1269.41
Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonis
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