| Bioactivity | Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[1][2]. | ||||||
| Invitro | Goserelin (1 nM-1 mM; 48-72 hours) promotes EOC cell apoptosis[1].Goserelin (100 μM; 24-72 hours) regulates the expression of human apoptosis-related genes in SKOV3-ip cells[1].Goserelin (100 μM; 24-72 hours) promotes EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway[1]. Apoptosis Analysis[1] Cell Line: | ||||||
| Name | Goserelin acetate | ||||||
| CAS | 145781-92-6 | ||||||
| Formula | C61H88N18O16 | ||||||
| Molar Mass | 1329.46 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Goserelin acetate
CAS: 145781-92-6 F: C61H88N18O16 W: 1329.46
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions
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