Bioactivity | Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2]. |
Invitro | Gochnatiolide A (0.25-250 μg/mL; 48 h) 抑制细胞生长,对 786.0,UACC-62,NCI-ADR/RES,U251,MCF-7,NCI-H460,HT-29,PC-3,OVCAR-3,VERO 和 K562 细胞的 TGI (总生长抑制) 值分别为 0.42,0.49,0.70,1.09,1.69,4.66,5.42,6.63,54.73,13.13 和 114.87 μg/mL[2] 。 |
Name | Gochnatiolide A |
CAS | 87606-12-0 |
Formula | C30H30O7 |
Molar Mass | 502.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xiong HP, et, al. A dimeric sesquiterpene, gochnatiolide A. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2847. [2]. Strapasson RLB, et, al. Bioactivity-guided isolation of cytotoxic sesquiterpene lactones of Gochnatia polymorpha ssp. Floccose. Phytother Res. 2012 Jul;26(7):1053-6. |