PeptideDB

Gochnatiolide A

CAS: 87606-12-0 F: C30H30O7 W: 502.56

Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiprolifera
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Bioactivity Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].
Invitro Gochnatiolide A (0.25-250 μg/mL; 48 h) 抑制细胞生长,对 786.0,UACC-62,NCI-ADR/RES,U251,MCF-7,NCI-H460,HT-29,PC-3,OVCAR-3,VERO 和 K562 细胞的 TGI (总生长抑制) 值分别为 0.42,0.49,0.70,1.09,1.69,4.66,5.42,6.63,54.73,13.13 和 114.87 μg/mL[2] 。
Name Gochnatiolide A
CAS 87606-12-0
Formula C30H30O7
Molar Mass 502.56
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Xiong HP, et, al. A dimeric sesquiterpene, gochnatiolide A. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2847. [2]. Strapasson RLB, et, al. Bioactivity-guided isolation of cytotoxic sesquiterpene lactones of Gochnatia polymorpha ssp. Floccose. Phytother Res. 2012 Jul;26(7):1053-6.