| Bioactivity | GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1]. |
| Invitro | GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2].GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50 value of 0.25 nM[2]. |
| Name | GnRH Associated Peptide (1-24), human |
| CAS | 148943-65-1 |
| Shortening | DAENLIDSFQEIVKEVGQLAETQR |
| Formula | C117H190N32O43 |
| Molar Mass | 2732.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
GnRH Associated Peptide (1-24), human
CAS: 148943-65-1 F: C117H190N32O43 W: 2732.95
GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fr
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