PeptideDB

Glyphosate isopropylammonium

CAS: 38641-94-0 F: C6H17N2O5P W: 228.18

Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative
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Bioactivity Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate isopropylammonium inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate isopropylammonium induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders[1][2][3].
Invitro Glyphosate isopropylammonium 暴露可通过产生氧化应激和早期细胞凋亡来干扰小鼠卵母细胞的成熟。Glyphosate isopropylammonium 诱导小鼠卵母细胞的早期细胞凋亡和自噬[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Glyphosate isopropylammonium 相关抗体:
CAS 38641-94-0
Formula C6H17N2O5P
Molar Mass 228.18
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208. [2]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435. [3]. Carmen Costas-Ferreira, et al. Toxic Effects of Glyphosate on the Nervous System: A Systematic Review. Int J Mol Sci. 2022 Apr 21;23(9):4605.