| Bioactivity | Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems[1]. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln)[2]. | ||||||||||||
| Invitro | Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide. Glycyl-glutamine (Glycyl-L-glutamine) has an advantage over free glutamine (Gln) as growth factors for cell culture during both autoclaving and storage[2]. | ||||||||||||
| In Vivo | Glycyl-glutamine (Glycyl-L-glutamine) (0.3, 0.6, 1.0 and 10.0 nM) can dose-dependently inhibit beta-End-(1-31)-induced hypotension in pentobarbital-anesthetized rats[1]. | ||||||||||||
| Name | Glycyl-glutamine | ||||||||||||
| CAS | 13115-71-4 | ||||||||||||
| Formula | C7H13N3O4 | ||||||||||||
| Molar Mass | 203.20 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8 [2]. Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8. |
Glycyl-glutamine
CAS: 13115-71-4 F: C7H13N3O4 W: 203.20
Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous anta
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