PeptideDB

Glycyl H-1152 hydrochloride

CAS: 913844-45-8 F: C18H26Cl2N4O3S W: 449.40

Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl
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Bioactivity Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride[1].
Name Glycyl H-1152 hydrochloride
CAS 913844-45-8
Formula C18H26Cl2N4O3S
Molar Mass 449.40
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Tamura M, et, al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30; 1754(1-2): 245-52.