Bioactivity | Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer[1][2]. |
Invitro | Glychionide A (3.12-100 μM) significantly inhibits the proliferation of the PANC-1 pancreatic cancer cells, with an IC50 of 14 μM[1].Glychionide A (7-28 μM) induces both autophagy and apoptosis in pancreatic cancer cells[1].Glychionide A (7-28 μM) causes G2/M arrest of PANC-1 pancreatic cancer cells[1].Glychionide A (7-28 μM) causes generation of ROS in PANC-1 cells[1]. |
Name | Glychionide A |
CAS | 119152-50-0 |
Formula | C21H18O11 |
Molar Mass | 446.36 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |