| Bioactivity | Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection [1][2]. |
| Invitro | Gly-Pro-Glu (0-100 μM) potentiates the potassium evoked release of both acetylcholine and dopamine, increases K+ evoked acetylcholine release even at concentrations of 0.1 nM and significantly enhances evoked dopamine release[1].Gly-Pro-Glu (1-1000 μM) shows an inhibition of L-[3H]glutamate binding with an IC50 value of 14.7 μM[1]. |
| Name | Gly-Pro-Glu |
| CAS | 32302-76-4 |
| Formula | C12H19N3O6 |
| Molar Mass | 301.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Gly-Pro-Glu
CAS: 32302-76-4 F: C12H19N3O6 W: 301.30
Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripep
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