| Bioactivity | Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM[1] | ||||||
| Invitro | Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2]. | ||||||
| Name | Gly-Arg-Gly-Asp-Ser | ||||||
| CAS | 96426-21-0 | ||||||
| Sequence | Gly-Arg-Gly-Asp-Ser | ||||||
| Shortening | GRGDS | ||||||
| Formula | C17H30N8O9 | ||||||
| Molar Mass | 490.47 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Gly-Arg-Gly-Asp-Ser
CAS: 96426-21-0 F: C17H30N8O9 W: 490.47
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp
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