Bioactivity | Glutathione arsenoxide (GSAO) TFA is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide TFA targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide TFA causes cell proliferation arrest and cell death. Glutathione arsenoxide TFA can be used to identify cell-surface proteins, such as Protein disulphide isomerase[1][2]. |
Formula | C20H26AsF3N4O11S |
Molar Mass | 662.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Park D, et al. The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell Int. 2012 Mar 26;12(1):11. [2]. Habeck M. Australian scientists design novel antiangiogenic weapon[J]. The Lancet Oncology, 2000, 1(4): 199. |