| Bioactivity | Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1]. |
| Invitro | Glucocorticoid receptor-IN-1 (Compound WX002) shows inhibitory effect on CYP3A4 with an IC50 of 16.7 µM[1]. |
| Name | Glucocorticoid receptor-IN-1 |
| CAS | 2662908-25-8 |
| Formula | C24H19F4N7O2 |
| Molar Mass | 513.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guoli Zhang, et al. Benzo[d][1,2,3]triazole ether compound. WO2021136431. |
Glucocorticoid receptor-IN-1
CAS: 2662908-25-8 F: C24H19F4N7O2 W: 513.45
Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammato
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.