| Bioactivity | Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1]. |
| Target | Ki: 32 nM (glucagon receptor) |
| Name | Glucagon receptor antagonists-5 |
| CAS | 2200274-63-9 |
| Formula | C30H29ClF3N3O3 |
| Molar Mass | 572.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu G, et al. Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126668. |
Glucagon receptor antagonists-5
CAS: 2200274-63-9 F: C30H29ClF3N3O3 W: 572.02
Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor anta
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