| Bioactivity | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation[2][3]. | ||||||
| Invitro | Upon binding to its receptor Gcgr, Glucagon activates cAMP-PKA signaling to stimulate hepatic glucose production (HGP) and cause hyperglycemia[1]. Glucagon stimulates both hepatic kisspeptin1 production and gluconeogenesis[1].Glucagon (100 nM) represses CYP7A1 mRNA expression in human primary hepatocytes[3].Glucagon (100 nM) increases phosphorylayion of HNF4α[3]. Western Blot Analysis[3] Cell Line: | ||||||
| Name | Glucagon (1-29), bovine, human, porcine | ||||||
| CAS | 16941-32-5 | ||||||
| Sequence | His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr | ||||||
| Shortening | HSQGTFTSDYSKYLDSRRAQDFVQWLMNT | ||||||
| Formula | C153H225N43O49S | ||||||
| Molar Mass | 3482.75 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Glucagon (1-29), bovine, human, porcine
CAS: 16941-32-5 F: C153H225N43O49S W: 3482.75
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluco
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