Glucagon (1-29), bovine, human, porcine hydrochloride_product_DataBase

Bioactivity	Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation[2][3].
Invitro	Upon binding to its receptor Gcgr, Glucagon activates cAMP-PKA signaling to stimulate hepatic glucose production (HGP) and cause hyperglycemia[1]. Glucagon stimulates both hepatic kisspeptin1 production and gluconeogenesis[1].Glucagon (100 nM) represses CYP7A1 mRNA expression in human primary hepatocytes[3].Glucagon (100 nM) increases phosphorylayion of HNF4α[3]. Western Blot Analysis[3] Cell Line:
Name	Glucagon (1-29), bovine, human, porcine hydrochloride
CAS	28270-04-4
Sequence	His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
Shortening	HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
Formula	C153H225N43O49S.ClH
Molar Mass	3519.21
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB