| Bioactivity | Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of macrophages and the immune functions of other immune cells [1]. Gliotoxin inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis[2]. Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus internalization into lung epithelial cells[3]. | |||||||||
| Name | Gliotoxin | |||||||||
| CAS | 67-99-2 | |||||||||
| Formula | C13H14N2O4S2 | |||||||||
| Molar Mass | 326.39 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
Gliotoxin
CAS: 67-99-2 F: C13H14N2O4S2 W: 326.39
Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.