| Bioactivity | Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate binds to human SMO (amino acids 181-787) with IC50value of 4 nM[1]. |
| Name | Glasdegib maleate |
| CAS | 2030410-25-2 |
| Formula | C25H26N6O5 |
| Molar Mass | 490.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sadarangani A, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. J Transl Med. 2015 Mar 21;13:98. |
Glasdegib maleate
CAS: 2030410-25-2 F: C25H26N6O5 W: 490.51
Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate bind
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