| Bioactivity | Glasdegib hydrochloride is a potent and orally bioavailable smoothened inhibitor. Glasdegib hydrochloride (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM[1]. |
| CAS | 1095173-64-0 |
| Formula | C21H23ClN6O |
| Molar Mass | 410.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sadarangani A, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. J Transl Med. 2015 Mar 21;13:98. |
Glasdegib hydrochloride
CAS: 1095173-64-0 F: C21H23ClN6O W: 410.90
Glasdegib hydrochloride is a potent and orally bioavailable smoothened inhibitor. Glasdegib hydrochloride (PF-04449913)
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