| Bioactivity | Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway[1][2][3]. | ||||||||||||
| Invitro | Genistin causes negative regulation of ERα. Genistin also effectively down-modulates ER nuclear translocation as well DNA binding activity in breast cancer cells. Moreover, GS effectively induced apoptosis and suppressed levels of oncogenic markers in MCF-7 cells[3]. | ||||||||||||
| Name | Genistin | ||||||||||||
| CAS | 529-59-9 | ||||||||||||
| Formula | C21H20O10 | ||||||||||||
| Molar Mass | 432.38 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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