Geissoschizoline

CAS: 18397-07-4 F: C19H26N2O W: 298.42

Geissoschizoline ((+)-Geissoschizoline) is a potent inhibitor of human AChE/BChE, with IC50s of 20.40 µM and 10.21 µM,

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Bioactivity	Geissoschizoline ((+)-Geissoschizoline) is a potent inhibitor of human AChE/BChE, with IC50s of 20.40 µM and 10.21 µM, respectively. Geissoschizoline emerges as a possible multi-target prototype that can be very useful in studies of preventing neurodegeneration and restoring neurotransmission. Geissoschizoline aiso is a potent anti-inflammatory agent[1].
Invitro	Geissoschizoline(1 μM; 48 hours) significantly reduces production of TNF-α and NO in LPS-stimulated microglial cells [1].Geissoschizoline(1, 10 and 30 μM; 24 hours) shows no cytotoxicity to LPS-stimulated microglial cells[1] Cell Viability Assay[1] Cell Line:
Name	Geissoschizoline
CAS	18397-07-4
Formula	C19H26N2O
Molar Mass	298.42
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.