Ganglioside GD3 disodium salt_product_DataBase

CAS: 497932-19-1 F: C70H123N3Na2O29 W: 1516.71

Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of m

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Bioactivity	Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].
Invitro	Ganglioside GD3 is highly expressed in melanomas in comparison with melanocytes, is exclusively expressed in the early developmental stage of the fetal brain, and is highly expressed in activated T lymphocytes and in T cell malignant tumor cells suggest that GD3 is involved in tumor phenotypes, such as enhanced proliferation and frequent metastasis[1].
Name	Ganglioside GD3 disodium salt
CAS	497932-19-1
Formula	C70H123N3Na2O29
Molar Mass	1516.71
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6.

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