| Bioactivity | Ganglioside GD1a modulates toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Ganglioside GD1a significantly reduces the effect of LPS on the decrease of cell survival and on stimulation of reactive oxygen species production[1]. |
| CAS | 12707-58-3 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Svetlana Nikolaeva, et al. GM1 and GD1a gangliosides modulate toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Biochim Biophys Acta. 2015 Mar;1851(3):239-47. |