| Bioactivity | Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 μM and has good antiviral effects against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition[1]. |
| CAS | 86761-38-8 |
| Formula | C9H16N5O13P3 |
| Molar Mass | 495.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Polymeric Nanovectors Incorporated with Ganciclovir and HSV- tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy |
Ganciclovir triphosphate
CAS: 86761-38-8 F: C9H16N5O13P3 W: 495.17
Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovi
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