| Bioactivity | Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-1 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1]. |
| Target | Gamma-Glutamyl Transferase |
| Name | Gamma-Glutamyl Transferase-IN-1 |
| Formula | C19H14FN5O2 |
| Molar Mass | 363.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sheng T, et al. Chromatography-Free Synthesis of 尾-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056. |
Gamma-Glutamyl Transferase-IN-1
CAS: F: C19H14FN5O2 W: 363.35
Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial
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