| Bioactivity | Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles[1][2][3]. |
| Name | Gal-C4-Chol |
| CAS | 219850-70-1 |
| Formula | C40H69N3O7S |
| Molar Mass | 736.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [2]. Managit C, et al. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci. 2005 Oct;94(10):2266-75. [3]. Kawakami S, et al. Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochim Biophys Acta. 2000 Dec 15;1524(2-3):258-65. |
Gal-C4-Chol
CAS: 219850-70-1 F: C40H69N3O7S W: 736.06
Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein recepto
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