| Bioactivity | Gadobutrol (ZK 135079) hydrate is a nonionic paramagnetic macrocyclic gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI)[1]. |
| Invitro | Gadobutrol hydrate leads to a gradual decrease in cell density with increasing concentration under neutron irradiation[1]. Cell Viability Assay[1] Cell Line: |
| In Vivo | Gadobutrol hydrate (intravenous injection, 200 mM, once) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice[2]. Animal Model: |
| Name | Gadobutrol hydrate |
| CAS | 198637-52-4 |
| Formula | C18H33GdN4O10 |
| Molar Mass | 622.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. B Hofmann, et al. Gadolinium neutron capture therapy (GdNCT) of melanoma cells and solid tumors with the magnetic resonance imaging contrast agent Gadobutrol. Invest Radiol. 1999 Feb;34(2):126-33. [2]. Takashi Watanabe, et al. Gadobutrol enhances T1-weighted MRI of nerve cells. Toxicol Lett. 2019 Jun 15;308:17-2 |
Gadobutrol hydrate
CAS: 198637-52-4 F: C18H33GdN4O10 W: 622.73
Gadobutrol (ZK 135079) hydrate is a nonionic paramagnetic macrocyclic gadolinium-based contrast agent that can be used f
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