| Bioactivity | GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1]. |
| Name | GX-674 |
| CAS | 1432913-36-4 |
| Formula | C21H13ClF2N6O3S2 |
| Molar Mass | 534.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ahuja S, et al. Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. Science. 2015 Dec 18;350(6267):aac5464. |
GX-674
CAS: 1432913-36-4 F: C21H13ClF2N6O3S2 W: 534.95
GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50
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