| Bioactivity | GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth[1][2][3]. | ||||||||||||
| Invitro | GW-441756 (1 µM; 48 hours; spinal cord neurons cells) abolishs BmK NSPK-induced neurite outgrowth[1].GW-441756 (1 µM; 4 hours; PC12 cells) inhibits nerve growth factor induced neurite outgrowth[1]. Immunofluorescence[1] Cell Line: | ||||||||||||
| Name | GW 441756 | ||||||||||||
| CAS | 504433-23-2 | ||||||||||||
| Formula | C17H13N3O | ||||||||||||
| Molar Mass | 275.30 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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