| Bioactivity | GSTP1-1 inhibitor 2 (Compound 5g) is an hGSTP1-1 (glutathione S-transferase P1-1) inhibitor with an IC50 value of 12.2 μM. GSTP1-1 inhibitor 2 exhibits significant cytotoxicity against DU-145, PC3, and MCF-7 cell lines, with CC50 values of 36.6 μM, 11.9 μM, and 17.4 μM, respectively. It can be used in cancer research[1]. |
| Formula | C24H16ClNO5S |
| Molar Mass | 465.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sabt A, et al. Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors. PLoS One. 2024 Aug 14;19(8):e0306124. |