| Bioactivity | GSPT1 degrader-3 (Pro-2) is a CRBN-based PROTAC degrader for BRD, with a DC50 of 21.1 nM (4h)[1]. |
| Name | GSPT1 degrader-3 |
| Formula | C39H41ClN8O4S |
| Molar Mass | 753.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Christine M Arndt, et al. One-Pot Synthesis of Cereblon Proteolysis Targeting Chimeras via Photoinduced C(sp2)-C(sp3) Cross Coupling and Amide Formation for Proteolysis Targeting Chimera Library Synthesis. J Med Chem. 2023 Dec 28;66(24):16939-16952. |