| Bioactivity | GSK729 is a THPP inhibitor with the activity of inhibiting EchA6 and inhibiting Mycobacterium tuberculosis. GSK729 can selectively pull down EchA6 in a stereospecific manner, inhibit its activity, inhibit fatty acid synthesis of Mycobacterium tuberculosis, and has a bactericidal effect in a mouse chronic tuberculosis infection model. |
| CAS | 1403602-92-5 |
| Formula | C16H16F3N3O2 |
| Molar Mass | 339.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria |
GSK729
CAS: 1403602-92-5 F: C16H16F3N3O2 W: 339.31
GSK729 is a THPP inhibitor with the activity of inhibiting EchA6 and inhibiting Mycobacterium tuberculosis. GSK729 can s
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