| Bioactivity | GSK3β-peptide is a substrate mimetic peptide of glycogen synthase kinase 3-β (GSK3-β) that can bind to the active site of GSK3-β and mimic the behavior of a real substrate. GSK3β-peptide can be used to develop substrate mimetic inhibitors of Akt as potential anticancer drugs[1]. |
| CAS | 496856-73-6 |
| Sequence | Gly-Arg-Pro-Arg-Thr-Thr-Ser-Phe-Ala-Glu |
| Shortening | GRPRTTSFAE |
| Formula | C47H76N16O16 |
| Molar Mass | 1121.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kayser, et al. "Modifications of the GSK3β substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics." Bioorganic & medicinal chemistry letters 17.7 (2007): 2068-2073. |
GSK3β-peptide
CAS: 496856-73-6 F: C47H76N16O16 W: 1121.20
GSK3β-peptide is a substrate mimetic peptide of glycogen synthase kinase 3-β (GSK3-β) that can bind to the active sit
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