Bioactivity | GSK3β inhibitor II is an inhibitor of GSK3β. GSK3β inhibitor II can be used for research of Alzheimer’s disease (AD)[1]. | |||||||||
Invitro | GSK3β inhibitor II 与 Ile62、Phe67、Val70、Ala83 和 Leu188 具有疏水相互作用,与 Lys85 具有离子相互作用,以及与 Lys85 和 Val135 残基具有氢键相互作用[1]。GSK3β inhibitor II 与 Val135[1] 形成氢键。 | |||||||||
Name | GSK3β inhibitor II | |||||||||
CAS | 478482-75-6 | |||||||||
Formula | C14H10IN3OS | |||||||||
Molar Mass | 395.22 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Elangovan ND, et al. Screening of potential drug for Alzheimer's disease: a computational study with GSK-3 β inhibition through virtual screening, docking, and molecular dynamics simulation. J Biomol Struct Dyn. 2021 Nov;39(18):7065-7079. |