| Bioactivity | GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption[1].GSK2795039 reduces apoptosis[2]. | ||||||||||||
| Invitro | GSK2795039 (25 μM; 24 hours) reduces the combinatory effect of FeSO4 and LPS-increased levels of apoptosis and reduced the presence of caspase-3-positive PC12 cells[2]. Apoptosis Analysis[2] Cell Line: | ||||||||||||
| Name | GSK2795039 | ||||||||||||
| CAS | 1415925-18-6 | ||||||||||||
| Formula | C23H26N6O2S | ||||||||||||
| Molar Mass | 450.56 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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GSK2795039
CAS: 1415925-18-6 F: C23H26N6O2S W: 450.56
GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibi
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