| Bioactivity | GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis[1]. |
| Invitro | GSK1790627 (1、10 和 50 μM，60 分钟) 在重组 hNAT 酶存在下是稳定的[1]。 |
| Name | GSK1790627 |
| CAS | 871701-87-0 |
| Formula | C24H21FIN5O3 |
| Molar Mass | 573.36 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Ho MY, et al. Trametinib, a first-in-class oral MEK inhibitor mass balance study with limited enrollment of two male subjects with advanced cancers. Xenobiotica. 2014 Apr;44(4):352-68. |
GSK1790627
CAS: 871701-87-0 F: C24H21FIN5O3 W: 573.36
GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.