| Bioactivity | GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist, extracted from patent WO/2014154725A1, example 1. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 (hydrochloride) is 8.1, whereas its affinity in the cell Adhesion Assays was for: ανβ6 (pIC50 = 8.4); ανβ3 (pIC50 = 6); ανβ5 (pIC50 = 6.9); ανβ8 (pIC50 = 7.7). | ||||||||||||
| Target | pIC50 value: 8.4 (αvβ6). | ||||||||||||
| Name | GSK 3008348 hydrochloride | ||||||||||||
| CAS | 1629249-40-6 | ||||||||||||
| Formula | C29H38ClN5O2 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Anderson Niall Andrew, et al. Preparation of naphthyridine derivatives useful as αvβ6 integrin antagonists. From PCT Int. Appl. (2014), WO 2014154725 A1 20141002. |
GSK 3008348 hydrochloride
CAS: 1629249-40-6 F: C29H38ClN5O2 W:
GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist, extracted from patent WO/2014154725A1, example
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.