GSK-3/CDK5/CDK2-IN-1_product_DataBase

CAS: 395074-72-3 F: C21H22N4O2 W: 362.42

GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO20020101

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases[1].

Target

cdk5cdk2GSK-3

Invitro

GSK-3/CDK5/CDK2-IN-1 inhibits the phosphorylation of cdk5 peptide substrate phosphorylation, with an IC50 of less than about 50 μM[1].

Name

GSK-3/CDK5/CDK2-IN-1

CAS

395074-72-3

Formula

C21H22N4O2

Molar Mass

362.42

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Ahlijanian MK, et, al. Preparation of acylaminoimidazoles as inhibitors of cdk5, cdk2, and GSK-3. WO2002010141A1.

PeptideDB

GSK-3/CDK5/CDK2-IN-1

CAS: 395074-72-3 F: C21H22N4O2 W: 362.42