| Bioactivity | GSK-2250665A (Compound 13) is a selective Itk inhibitor with a pKi of 9.2. |
| Invitro | GSK-2250665A (Compound 13) achieves a pIC50 of 7.3 in the cell assay, measuring inhibition of IFNγ production from PBMCs (Peripheral Blood Mononuclear Cells) [1]. |
| Name | GSK-2250665A |
| CAS | 1246030-96-5 |
| Formula | C26H29N5OS |
| Molar Mass | 459.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alder CM, et al. Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy. ACS Med Chem Lett. 2013 Aug 12;4(10):948-52. |