| Bioactivity | GSK-1520489A is a PKMYT1 (active protein kinase) inhibitor (IC50=115 nM, Ki=10.94 nM)[1]. | ||||||||||||
| Target | IC50: 115 nM (PKMYT1) | ||||||||||||
| Invitro | GSK-1520489A (4 µM, 24 h) treatment shows inhibition of phosphorylation of Tyr15 in Cdk1[1]. Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | GSK-1520489A | ||||||||||||
| CAS | 1042433-41-9 | ||||||||||||
| Formula | C21H23N5O3S | ||||||||||||
| Molar Mass | 425.50 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Charlott Platzer, et al. Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II. Bioorg Med Chem. 2018 Aug 7;26(14):4014-4024. |