Bioactivity | GSI-18 is a γ-secretase inhibitor with anticancer activity. GSI-18 attenuates anchorage-independent growth in pancreatic cancer cells by inhibiting Notch signaling[1]. |
CAS | 362653-62-1 |
Formula | C17H19NO2S2 |
Molar Mass | 333.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mullendore, et al. "Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer." Clinical Cancer Research 15.7 (2009): 2291-2301. |